The church and the adjacent monastery are part of the Franciscan complex. Despite the war damage, many elements of the old equipment have been preserved in the temple: a baroque pulpit, 43-voice organs from 1925 and a painting by Matthias Kargen Stigmatization of Saint. Francis.
In the past, the site of the present temple was the first wooden Franciscan church who came to Warsaw in the 17th century. It was burnt down during the Swedish invasion. The monastery complex created in its place changed its functions. A tsar's orphanage for children was organized in the monastery, while the church served Catholics from the Russian army. The Franciscans regained the church and part of the buildings after the end of World War I, and the rest of the buildings housed the Polish Fiat factory.
During World War II, the temple was at the northeastern edge of the Warsaw Ghetto. It was bombed after the outbreak of the Warsaw Uprising. However, the side walls have survived, the altar of St. Anthony's and many elements of baroque equipment.