The Catacombs of Priscilla (Catacombe di Priscilla) in Rome is an underground cemetery carved in tuff (sedimentary rock). They are known for the velata cubiculum (burial chamber) with a well-preserved fresco from the 3rd century, depicting a woman in a prayer pose. An important discovery are also the first performances of the Mother of God and the Annunciation. Today, the entrance to the catacombs leads from the Catacombs of Priscilla House, the seat of the Benedictine Sisters.
A series of antique frescoes from the 2nd century were discovered in the Greek Chapel, known as the "early Christian Sistine Chapel," mainly from the Old Testament. The walls of the room are also covered with inscriptions in Greek.
The catacombs are 35 meters underground. Their name probably comes from the name of the woman who donated her land to build a new cemetery. In the third and fourth century, the remains of many martyrs were buried here, including Pope Marcellinus.